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When a nurse aide discovers a fire in a resident's room, the first action they should take is to remove the resident from the room. Ensuring the safety of individuals is the primary concern in an emergency situation like a fire. The potential for smoke inhalation, burns, or other injuries necessitates immediate action to protect residents from harm.

Once the resident is safely out of the danger zone, further actions can be taken, such as notifying others about the fire or attempting to extinguish it if safe to do so. The focus on moving the resident ensures they are prioritized and reduces the risk of panic or injury during a chaotic event.

Other actions, such as using water to put out the fire or opening a window, could potentially put the aide or the resident at greater risk. Yelling for help might also be necessary, but it should come after ensuring the resident's safety. Therefore, the correct approach is to prioritize the evacuation of the person in danger.